NAD+ 500mg
$50.00
Description
NAD⁺ (Nicotinamide Adenine Dinucleotide) is a universal redox coenzyme central to cellular metabolism, mitochondrial energy production, and DNA repair. It is a master regulator of sirtuin activation, PARP enzymes, and oxidative-stress balance—making it one of the most extensively studied molecules in longevity and metabolic research.
Mechanism of Action:
- Serves as an electron carrier in the NAD⁺/NADH cycle, fueling cellular respiration and ATP synthesis.
- Activates SIRT1–SIRT7 deacetylase enzymes, supporting gene-expression regulation and DNA repair.
- Enhances mitochondrial biogenesis, stem-cell maintenance, and telomere integrity.
Research Highlights:
NAD⁺ levels decline significantly with age; preclinical and clinical models demonstrate that restoration of NAD⁺ pools improves mitochondrial function, insulin sensitivity, and cognitive performance. Paired stimulation via NMN or 5-Amino-1MQ shows synergistic metabolic benefits.
References: PMID 32839402 | Cell Metab 2020 | Nature Aging 2021
Potential Applications (for research use):
- Cellular energy and mitochondrial function models
- Longevity and age-associated metabolic research
- DNA-repair and oxidative-stress studies
Stacking Callouts:
Frequently paired with 5-Amino-1MQ, MOTS-C, or KLOW for synergistic mitochondrial and cellular-recovery research protocols.
For laboratory and research use only. Not for human consumption.